Tamoxifen 20mg x 60 Tabs

Description

Tamoxifen 20mg x 60 Tabs

Tamoxifen 20mg x 60 Tabs is a selective estrogen receptor modulator (SERM) widely prescribed for breast cancer prevention and treatment. It is also utilized in post-cycle therapy (PCT) by athletes and bodybuilders to restore natural testosterone production after anabolic steroid use.

Classification of Tamoxifen 20mg x 60 Tabs

Tamoxifen belongs to the SERM class, meaning it can act as an estrogen antagonist in certain tissues (like breast tissue) and as a partial agonist in others (such as bone or endometrium).
Pharmacological classification: Antineoplastic agent, Hormone modulator.

What Is Tamoxifen 20mg x 60 Tabs?

Each tablet contains 20 milligrams of Tamoxifen citrate, the active compound responsible for blocking estrogen receptors. The pack of 60 tablets provides a 30–60 day supply, depending on prescribed dosage.

Common brand names: Nolvadex, Soltamox.

Pharmacological Profile and Drug Class

• Drug Type: Nonsteroidal anti-estrogen

• Form: Oral tablet

• Active Ingredient: Tamoxifen citrate

• Therapeutic Class: SERM

• Target: Estrogen receptor (ERα, ERβ)

Recommended Dosage for Tamoxifen 20mg x 60 Tabs

For breast cancer treatment, the usual adult dose is 20–40 mg per day, taken orally.
For post-cycle therapy, athletes often use 10–20 mg daily for 4–6 weeks.
Important: Only take Tamoxifen under medical supervision or after consulting a qualified healthcare provider.

How Does Tamoxifen 20mg x 60 Tabs Work?

Tamoxifen functions by binding to estrogen receptors, blocking the hormone estrogen from stimulating the growth of estrogen-dependent cancer cells.
In men, it helps restore natural testosterone production by reducing estrogen’s inhibitory effect on the hypothalamic-pituitary-gonadal axis.

Mechanism of Action Explained

Tamoxifen acts as an estrogen receptor antagonist in breast tissue. It prevents estrogen from binding to the receptor, inhibiting cancer cell proliferation.
However, in other tissues such as the bones, it acts as a partial agonist, helping maintain bone density in postmenopausal women.

Uses of Tamoxifen 20mg x 60 Tabs

• Treatment of estrogen receptor-positive (ER+) breast cancer

• Prevention of breast cancer in high-risk women

• Post-cycle therapy (PCT) in bodybuilding

• Gynecomastia prevention in men using anabolic steroids

Tamoxifen in Breast Cancer Treatment

Tamoxifen is a cornerstone in adjuvant therapy for ER-positive breast cancer.
Clinical trials show it reduces the risk of recurrence by up to 40% when used for 5 years after surgery

Tamoxifen in Post-Cycle Therapy (PCT)

After steroid cycles, natural testosterone levels drop. Tamoxifen stimulates LH (luteinizing hormone) and FSH (follicle-stimulating hormone), restoring hormonal balance.
Typical PCT dosage: 20 mg/day for 4 weeks.

Benefits of Tamoxifen 20mg x 60 Tabs

• Prevents breast cancer recurrence

• Restores hormonal equilibrium

• Reduces risk of gynecomastia

• Improves testosterone-to-estrogen ratio

• Supports postmenopausal bone health

When Should You Take Tamoxifen 20mg x 60 Tabs?

Take Tamoxifen once daily at the same time each day, preferably with food.
For PCT, start 3–5 days after your last steroid dose.

When Should You Not Take Tamoxifen 20mg x 60 Tabs?

Avoid Tamoxifen if you:

• Are pregnant or breastfeeding

• Have a history of blood clots or stroke

• Are allergic to Tamoxifen citrate

• Are taking certain anticoagulants (e.g., warfarin)

Warnings and Precautions

• Pregnancy risk: Tamoxifen may cause fetal harm.

• Liver function: Regular liver monitoring recommended.

• Ophthalmic effects: Possible visual disturbances.

• Thromboembolism: Increased risk of deep vein thrombosis.

Side Effects of Tamoxifen 20mg x 60 Tabs

Common side effects include:

• Hot flashes

• Fatigue

• Nausea

• Irregular menstruation
  Rare but serious:

• Liver abnormalities

• Endometrial cancer

• Thromboembolic events

Drug Interactions and Contraindications

Avoid combining with:

• Warfarin (increased bleeding risk)

• SSRIs (e.g., Paroxetine)

• Estrogen-containing medications

Storage Instructions for Tamoxifen 20mg x 60 Tabs

Store at 20°C–25°C (68°F–77°F) in a dry, cool place, away from sunlight.
Keep the container tightly closed and out of reach of children.

Where to Buy Tamoxifen 20mg x 60 Tabs in the UK

You can buy Tamoxifen 20mg x 60 Tabs from Steroids UK Outlet, a trusted online retailer offering authentic pharmaceutical-grade products.
Ensure you purchase from licensed sources to avoid counterfeit medications.

Legal Status and Prescription Information

In the UK, Tamoxifen is a prescription-only medicine (POM).
For research or bodybuilding purposes, it should only be acquired legally and used responsibly.

Tamoxifen for Bodybuilders and Athletes

Tamoxifen is commonly included in PCT stacks with Clomiphene Citrate (Clomid) to restore hormonal balance and maintain muscle gains post-cycle.

Tamoxifen vs Aromatase Inhibitors

While Aromatase Inhibitors (AIs) like Anastrozole block estrogen production, Tamoxifen blocks estrogen receptor binding.
Tamoxifen is often preferred for PCT due to its milder hormonal rebound.

Clinical Studies Supporting Tamoxifen Use

• The ATLAS trial demonstrated a 29% reduction in breast cancer mortality after 10 years of Tamoxifen use.

• The NSABP B-14 study confirmed its efficacy in ER-positive cases.

Common Myths About Tamoxifen

• Myth: Tamoxifen is a steroid.
  Fact: It is not; it’s a nonsteroidal SERM.

• Myth: It completely blocks estrogen.
  Fact: It selectively blocks estrogen in certain tissues only.

Tips for Safe and Effective Use

• Follow medical advice strictly.

• Do not exceed the recommended dosage.

• Regularly monitor liver and vision functions.

• Report any abnormal bleeding or pain to your doctor.

 Frequently Asked Questions (FAQ)

Q1: Can Tamoxifen be used by men?
A: Yes, especially in post-cycle therapy and to treat gynecomastia.

Q2: Is Tamoxifen safe for long-term use?
A: Generally, yes  under supervision. Some women take it for 5–10 years.

Q3: Can I drink alcohol while on Tamoxifen?
A: Moderate alcohol may be permissible but should be discussed with a doctor.

Q4: Does Tamoxifen cause weight gain?
A: Some users report minor changes, often due to hormonal balance shifts.

Q5: How long does it take to see results?
A: Effects on hormone balance are noticeable within 1–2 weeks of consistent use.

Tamoxifen 20mg x 60 Tabs remains a cornerstone therapy for managing estrogen-dependent breast cancers and an essential PCT tool in athletic recovery.
By understanding its mechanism, dosage, and safety profile, users can optimize its benefits while minimizing risks.